Performance of data serialization methods for wireless communication in resource-constrained devices

The present thesis aims at comparing the performance of the data serialization methods, JSON and EXI, as recommended in the Technical Specifications published by ETSI Machine-To-Machine Technical Committee. The objective is to evaluate the portability of ETSI M2M to constrained wireless sensor network devices measuring the messaging performance at the application layer. The evaluation has been performed using a ETSI M2M benchmarking service implemented on top of the full Internet of Things stack of protocols including CoAP, 6LoWPAN, and IEEE 802.15.

The genetic architecture of the human cerebral cortex

The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder